The association of CBD and glaucoma may be new. However, the medical community has known for years that cannabis helped to alleviate symptoms of glaucoma. New studies indicate that CBD may be just as effective as THC in treating glaucoma. In fact, CBD may be more effective than THC in treating certain aspects of glaucoma. Notwithstanding, many of the studies concerning CBD and glaucoma still include Delta9-tetrahydrocannabinol as a primary therapeutic agent.
Scientists associated glaucoma with elevated levels of glutamate. Glutamate is one of the most prevalent neurotransmitters in our nervous system. It is responsible for a variety of motor functions and cerebral activity. Too much glutamate causes damage to neurons, thus resulting in death of neurons and surrounding cells. It’s not surprising to learn that CBD oil for glaucoma would provide soothing relief.
CBD and glaucoma research was inspired by a theory that peroxynitrate was a contributing factor of retinal cell damage.
Scientists at the Department of Pharmacology and Toxicology in the Medical College of Georgia theorized that an increased production of glutamate was also indirectly involved with the death of retinal neurons. (https://www.ncbi.nlm.nih.gov/pubmed/14578199)
They believed that elevated levels of glutamate led to a heightened production of peroxynitrate. Peroxynitrate is a highly unstable salt. The CBD research team believed that the excess formation of peroxnitrate was the chief cause of retinal neurotoxicity.
The scientists not only proved the theory right, they also demonstrated that treatment with CBD helped to significantly decrease the production of peroxynitrate. Furthermore, they demonstrated that the neuroprotective qualities of CBD help to prevent excessive damage in areas where peroxynitrate was present.
Scientists were able to relieve intraocular pressure with CBD at higher administration levels.
The National Center for Biotechnology Information published a study regarding CBD and glaucoma. (https://www.ncbi.nlm.nih.gov/pubmed/16988594)
Medical researchers treated test subjects with a solution containing a low amount of THC and a high amount of CBD. At 20mg of CBD, there was no relief of intraocular pressure. However, when the medical team increased the CBD level to 40 mg, patients experienced a slight reduction in eye pressure.
While scientists have long recognized THC as a therapeutic treatment for glaucoma, they are just realizing the cell-enriching effects of CBD. Science is making much more headway with CBD and glaucoma may be another “CBD disease“.