CBD for Digestive Issues: A Broad Overview of a General Disorder

CBD for digestive issues…

Research regarding CBD for digestive issues indicates cannabis can provide the relief that millions of patients have been waiting for.  The term ‘digestive issues’ or ‘digestive disorders’ is extremely general.  However, millions of Americans and others around the globe suffer from a wide variety of digestive orders.  Among them are Crohn’s disease, irritable bowel syndrome, colitis, and a wide variety of other conditions related to the intestines and other gastrointestinal organs.


Research indicates that CBD for digestive issues is effective because of the relationship between the endocannabinoid system and the peroxisome proliferator-activated receptor-gamma gene.

Scientists in Italy have identified a connection between the endocannabinoid system and the regulation of the peroxisome proliferator-activated receptor-gamma gene. (https://www.ncbi.nlm.nih.gov/pubmed/22815234)

Medical professionals have long contained knowledge that the peroxisome proliferator-activated receptor-gamma gene is responsible for a variety of digestive and inflammatory conditions.  CBD for digestive issues provides a safe and natural means by which production of this gene can be regulated.

Fortunately, lab results show that CBD treatment relieves symptoms of and arrests the progression of gastrointestinal disorders.   Now that scientist know of the interaction between the endocannabinoid system and this destructive gene, a new wave of CBD therapies may be introduced to help prevent colitis, Crohn’s, IBS, and a variety of other digestive diseases.


CBD and Crohn’s disease is getting plenty of attention from the medical research community.

Scientists in the Institute of Experimental and Clinical Pharmacology in the Medical University of Graz in Graz, Austria released a placebo-controlled study regarding CBD and Crohn’s disease.  (https://www.ncbi.nlm.nih.gov/pubmed/24356243)


Medical researchers involved in the study concluded that CBD provided significant therapeutic relief to patients suffering from Crohn’s disease.


CBD for digestive issues also works by dominating the neuro-immune axis via the endocannabinoid system.

Scientists at the Department of Experimental Pharmacology in the University of Naples Federico II in Naples, Italy, released a study regarding CBD for digestive issues in mice.  (https://www.ncbi.nlm.nih.gov/pubmed/22163000)

The medical research team involved discovered that CBD caused receptors in the endocannabinoid system to communicate with the neuro-immune axis to regulate a variety of intestinal and cellular activity.  Consequently, CBD treatment was able to prevent intestinal inflammation in mice.  Scientists were also able to effectively use CBD to treat humans with ulcerative colitis.  Patients were suffering from negative effects of intestinal biopsies, and CBD helped preserve tissue and prevent inflammation and inflammatory damage.


Research concluded that CBD for digestive issues in mice helped to prevent experimental colitis.

Research conducted in Italy revealed that CBD is effective in protecting against the onset of colitis.  (https://www.ncbi.nlm.nih.gov/pubmed/19690824)

Lab technicians induced colitis in a group of rats.  However, CBD treatment prevented colitis infection.


CBD for digestive issues works not only by reducing inflammation, but by reducing the frequency of functional disturbances common with digestive disorders.

A research team in the School of Life Sciences at the University of Hertfordshire in the United Kingdom, conducted research on CBD for digestive issues. (https://www.ncbi.nlm.nih.gov/pubmed/20590574)

The goal of the study was to use CBD to reduce inflammation caused by irritable bowel disease.  They were not only successful in reducing inflammation, the research team was also successful in reducing the frequency of gastrointestinal distress with consistent CBD treatment.


CBD treatment was effective in reducing colonic inflammation in mice with colitis.

The National Institute for Biotechnology Information published a study regarding CBD for digestive issues.  (https://www.ncbi.nlm.nih.gov/pubmed/22414698)

In this study, researchers used CBD to treat colitis in mice.  Like the aforementioned study, CBD was successful in reducing colonic inflammation. Furthermore, CBD significantly improved the health condition of the mice by regulating all aspects of colitis.

There are a variety of other studies indicating that CBD was effective in treating different aspects of digestive issues.  NCBI published another study in which it was identified that the endocannabinoid system’s relationship to  GPR 55 and GRP 119 receptors may also play a significant role in arresting and reversing gastrointestinal damage caused by digestive disorders.  (https://www.ncbi.nlm.nih.gov/pubmed/20117132)

They also published information from a research team in Germany.  This team noted a series of impressive results with CBD for digestive issues. Their findings range from reduced gastric secretion and fewer gastrointestinal attacks to less severe inflammation and improved digestive performance.  (https://www.ncbi.nlm.nih.gov/pubmed/16751708)

Even more research supporting the efficacy of CBD for digestive issues was released by NCBI.  Not surprisingly, it demonstrates the power of CBD for digestive issues.



The role of CBD in the treatment of a wide variety of gastrointestinal and digestive disorders is growing significantly.  Correspondingly, CBD for digestive issues makes sense from a variety of scientific angles.

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