Endocannabinoid professionals say, “Yes!” to CBD for PTSD.
Studies on CBD for PTSD are in! Not surprisingly, scientists have linked the endocannabinoid system to a variety of fear and conditioning-based neurotransmitters that play an integral role in the persistence of PTSD.
What is PTSD? Furthermore, how can CBD for PTSD help?
According to the Mayo Clinic, PTSD, or posttraumatic stress disorder, is a condition of mental health. Individuals with PTSD either witnessed or experienced a highly traumatic or terrifying event. As a result, they suffer from anxiety, depression, hypervigilance, insomnia, and a variety of other fear or guilt-based conditions. Furthermore, patients with PTSD may have flashbacks and/or easily perceive danger when there is none.
Question of the day…How can CBD for PTSD help?
Funny you should ask! That happens to be what this article is about. In short, CBD for PTSD works by regulating a variety of neuro-receptors that control fear, memory, and a list of psychiatric-related neurotransmitters, such as dopamine, GABA, norepinephrine, and serotonin. In many of the studies related to CBD for PTSD, the medical researchers focus on perceptions and responses of fear to external stimuli.
Using CBD for PTSD enables medical professionals to modulate emotional learning exercises in a therapeutic environment, thus providing safe and effective therapy for PTSD.
A group of psychiatric and behavioral science researchers in Atlanta, GA, conducted a study on CBD for PTSD. (https://www.ncbi.nlm.nih.gov/pubmed/15637635)
In this study, endocannabinoid professionals induced production of a metabolite AM404 with CBD treatment in animals. They successfully reduced the reinstatement of fear with manipulation of the endocannabinoid system. Scientists conducting the study believe that CBD treatment for PTSD would have the same result in humans.
CBD for PTSD may work by increasing the level of n-3 long-chain polyunsaturated fatty acid.
Scientists in Austria and Japan collaborated on a study related to CBD for PTSD. (https://www.ncbi.nlm.nih.gov/pubmed/24518289)
More specifically, they were studying the manner in which CBD would increase production of n-3 long-chain polyunsaturated fatty acid. Not to that end alone, though. They wanted do understand if this fatty acid even played a role in fear memory, in the first place.
For some time, psychiatric professionals have linked this fatty acid to improved psychiatric conditions like depression and anxiety. In this particular study, lab technicians used a variety of diets with CBD for PTSD to stimulate healthy production of n-3 long-chain polyunsaturated fatty acid in mice. They successfully answered both questions. Yes, n-3 long-chain polyunsaturated fatty acid is linked to fear memory. Yes, healthy endocannabinoid activity results in increased production of n-3 long-chain polyunsaturated fatty acid, thus helping to recondition fear memories in a safe and therapeutic environment.
Studies with CBD for PTSD show that cannabinoids help to mitigate behavioral responses to perceived, fear-inducing threats.
A group of pharmacology professionals in Brazil conducted research concerning CBD for PTSD. (https://www.ncbi.nlm.nih.gov/pubmed/22979992)
Much in line with other endocannabinoid research, this team of investigators identified the role of the 5-HT1A receptor in behavior modifications on fear-based reactions. Endocannabinoid professionals conducing research on CBD and depression had already identified the role of the endocannabinoid system and the 5-HT1A neurotransmitter in treating psychiatric conditions.
CBD for PTSD may actually be successful in abolishing fears completely.
A team of psychiatric professionals in Michigan prepared literature concerning CBD for PTSD (https://www.ncbi.nlm.nih.gov/pubmed/23829364)
In this documentation, researchers point out that the endocannabinoid system is directly linked to neural circuits that host fears and memories. Cannabinoids could be used to modulate activity in those circuits, thereby abolishing fears in patients suffering from PTSD.
Researchers in Israel released similar publication. (https://www.ncbi.nlm.nih.gov/pubmed/23433741)
In this piece, however, professionals get even more specific about the amygdala-hippocampal-prefrontal circuit. This isn’t the first study in which endocannabinoid professionals have identified the endocannabinoid system’s connection to this region of the brain in relation to managing psychiatric symptoms. As a matter of fact, it’s one of many!
Scientists and endocannabinoid professionals may not always agree on everything cannabis related. However, they all seem to agree that CBD for PTSD works. Although this may be true, it may still be some time before each state’s CBD laws catch up to science.