Science Supports CBD oil for pain management and possibly even prevention.
CBD oil for pain management may replace opiate drugs and even standard over-the-counter pain killers. Unlike opiates, CBD is safe for all ages. CBD also has very few negative side effects is well tolerated by all age and demographic groups. Let’s take a scientific look at how the endocannabinoid system relates to pain.
Understanding the Endocannabinoid System
The Endocannabinoid System is a highly complex system throughout the body. It responds to cannabinoids and other compounds found in cannabis. Once activated by cannabis, the Endocannabinoid System unlocks thousands of otherwise inactive proteins, molecules, neurotransmitters, and other highly therapeutic processes. These affect all parts of the body in one way or another.
The endocannabinoid system is linked directly to the central nervous system (https://www.ncbi.nlm.nih.gov/pubmed/10462067) and the peripheral nervous system (https://www.ncbi.nlm.nih.gov/pubmed/14499415), and pain is nerve-based reaction (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438523/).
CBD is effective for pain management, because it activates these dormant physiological agents.
CBD inhibits adenosine transporters. Then, CBD is able to modify signaling to the A2A adenosine receptor to mediate pain (https://www.ncbi.nlm.nih.gov/pubmed/16672367). Martin WJ, et al, identified that CBD for pain management was 10 times more effective than morphine (https://www.ncbi.nlm.nih.gov/pubmed/8815936).
CBD oil for pain management (including chronic pain and neuropathic pain) study involving rats.
The Journal of Experimental Medicine published a study concerning CBD for pain management. It tested the efficacy and tolerability of CBD for pain management in mice and rats. The study focused on inflammation and neuropathic pain. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371734/)
Mice in the study tolerated CBD treatments very well. CBD was effective in reducing inflammation. CBD for pain management specifically also proved to be effective.
Knowledge and research of CBD is evolving!
Scientists everywhere seem to be accepting that CBD is a highly effective medicinal agent. Even more scientists agree that CBD is safe for human consumption among all ages. The research now is helping to increase our understanding of the endocannabinoid system. This will help to improve knowledge of best CBD dosage for pain, best CBD oil for pain, and the manner in which various intake methods of CBD oil (for pain management or any other therapeutic benefit) trigger biological activity in different ways.